AJP - Lung Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Lung Cell Mol Physiol 263: L617-L618, 1992;
1040-0605/92 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Chinard, F. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chinard, F. P.

AJP - Lung Cellular and Molecular Physiology, Vol 263, Issue 6 617-L618, Copyright © 1992 by American Physiological Society

ARTICLES

Quantitative assessment of epithelial lining fluid in the lung

F. P. Chinard
Department of Medicine, University of Medicine and Dentistry, New Jersey Medical School, Newark 07103.

Current techniques for the measurement lung epithelial fluid (ELF) volume depend on the dilution by a known volume of wash fluid (bronchoalveolar lavage) of a resident solute, such as urea, in the ELF or of a foreign solute introduced at known concentration in the lavage fluid. Knowledge of the ELF volume allows calculation of solute ELF concentrations. Urea concentration in ELF is assumed to be the same as in plasma. Although epithelial permeability to urea is low, entry of urea from tissues to lavage fluid occurs during the procedure and may lead to erroneous estimates of ELF volume as may loss of foreign solutes. Ideally, the extent of urea entry or of foreign solute loss should be estimated in each lavage. Other cautions are 1) equal osmolality of wash fluid and plasma, 2) minimizing residence time of wash fluid, 3) minimizing wash fluid-to-ELF volume ratio, and 4) adequate analytic procedures.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
R. Summer, F. F. Little, N. Ouchi, Y. Takemura, T. Aprahamian, D. Dwyer, K. Fitzsimmons, B. Suki, H. Parameswaran, A. Fine, et al.
Alveolar macrophage activation and an emphysema-like phenotype in adiponectin-deficient mice
Am J Physiol Lung Cell Mol Physiol, June 1, 2008; 294(6): L1035 - L1042.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
C. Kariya, H. Leitner, E. Min, C. van Heeckeren, A. van Heeckeren, and B. J. Day
A role for CFTR in the elevation of glutathione levels in the lung by oral glutathione administration
Am J Physiol Lung Cell Mol Physiol, June 1, 2007; 292(6): L1590 - L1597.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
L. W. Velsor, A. van Heeckeren, and B. J. Day
Antioxidant imbalance in the lungs of cystic fibrosis transmembrane conductance regulator protein mutant mice
Am J Physiol Lung Cell Mol Physiol, July 1, 2001; 281(1): L31 - L38.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
N. E. AVISSAR, C. K. REED, C. COX, M. W. FRAMPTON, and J. N. FINKELSTEIN
Ozone, But Not Nitrogen Dioxide, Exposure Decreases Glutathione Peroxidases in Epithelial Lining Fluid of Human Lung
Am. J. Respir. Crit. Care Med., October 1, 2000; 162(4): 1342 - 1347.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
R. E. T. NOCKER, F. R. WELLER, T. A. OUT, M. J. de RIEMER, H. M. JANSEN, and J. S. van der ZEE
A Double-blind Study on the Effect of Inhaled Corticosteroids on Plasma Protein Exudation in Asthma
Am. J. Respir. Crit. Care Med., May 1, 1999; 159(5): 1499 - 1505.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online