INVITED REVIEW:

Michael S. Wolin, Mansoor Ahmad, and Sachin A. Gupte

Oxidant and redox signaling in vascular oxygen sensing mechanisms: basic concepts, current controversies, and potential importance of cytosolic NADPH
Am J Physiol Lung Cell Mol Physiol 289: L159-L173, 2005; doi:10.1152/ajplung.00060.2005 [Abstract] [Full Text] [PDF]  

EDITORIAL FOCUS:

Dolly Mehta

Lysophosphatidylcholine: an enigmatic lysolipid
Am J Physiol Lung Cell Mol Physiol 289: L174-L175, 2005; doi:10.1152/ajplung.00165.2005 [Full Text] [PDF]  

Fei Huang, Papasani V. Subbaiah, Oksana Holian, Jihang Zhang, Arnold Johnson, Nancy Gertzberg, and Hazel Lum

Lysophosphatidylcholine increases endothelial permeability: role of PKC and RhoA cross talk
Am J Physiol Lung Cell Mol Physiol 289: L176-L185, 2005. First published March 11, 2005; doi:10.1152/ajplung.00003.2005 [Abstract] [Full Text] [PDF]  

ARTICLES:

Celine A. Beamer and Andrij Holian

Scavenger receptor class A type I/II (CD204) null mice fail to develop fibrosis following silica exposure
Am J Physiol Lung Cell Mol Physiol 289: L186-L195, 2005. First published April 22, 2005; doi:10.1152/ajplung.00474.2004 [Abstract] [Full Text] [PDF]  

Bing Zhu, Samuel Strada, and Troy Stevens

Cyclic GMP-specific phosphodiesterase 5 regulates growth and apoptosis in pulmonary endothelial cells
Am J Physiol Lung Cell Mol Physiol 289: L196-L206, 2005. First published March 25, 2005; doi:10.1152/ajplung.00433.2004 [Abstract] [Full Text] [PDF]  

Thomas A. Russo, Bruce A. Davidson, Stacy A. Genagon, Natalie M. Warholic, Ulrike MacDonald, Patrick D. Pawlicki, Janet M. Beanan, Ruth Olson, Bruce A. Holm, and Paul R Knight, III

E. coli virulence factor hemolysin induces neutrophil apoptosis and necrosis/lysis in vitro and necrosis/lysis and lung injury in a rat pneumonia model
Am J Physiol Lung Cell Mol Physiol 289: L207-L216, 2005. First published April 1, 2005; doi:10.1152/ajplung.00482.2004 [Abstract] [Full Text] [PDF]  

John H. Tinsley, Jerome W. Breslin, Nicole R. Teasdale, and Sarah Y. Yuan

PKC-dependent, burn-induced adherens junction reorganization and barrier dysfunction in pulmonary microvascular endothelial cells
Am J Physiol Lung Cell Mol Physiol 289: L217-L223, 2005. First published April 8, 2005; doi:10.1152/ajplung.00248.2004 [Abstract] [Full Text] [PDF]  

Thomas G. Brock, Young-Jik Lee, Elana Maydanski, Tessa L. Marburger, Ming Luo, Robert Paine, III, and Marc Peters-Golden

Nuclear localization of leukotriene A₄ hydrolase in type II alveolar epithelial cells in normal and fibrotic lung
Am J Physiol Lung Cell Mol Physiol 289: L224-L232, 2005. First published April 1, 2005; doi:10.1152/ajplung.00423.2004 [Abstract] [Full Text] [PDF]  

Stewart J. Levine, Barbara Adamik, Feras I. Hawari, Aminul Islam, Zu-Xi Yu, Da-Wei Liao, Jing Zhang, Xinle Cui, and Farshid N. Rouhani

Proteasome inhibition induces TNFR1 shedding from human airway epithelial (NCI-H292) cells
Am J Physiol Lung Cell Mol Physiol 289: L233-L243, 2005. First published April 8, 2005; doi:10.1152/ajplung.00469.2004 [Abstract] [Full Text] [PDF]  

Erica L. Martin, Lynda A. McCaig, Brent Z. Moyer, M. Cynthia Pape, Kevin J. Leco, James F. Lewis, and Ruud A. W. Veldhuizen

Differential response of TIMP-3 null mice to the lung insults of sepsis, mechanical ventilation, and hyperoxia
Am J Physiol Lung Cell Mol Physiol 289: L244-L251, 2005. First published April 1, 2005; doi:10.1152/ajplung.00070.2005 [Abstract] [Full Text] [PDF]  

Kai Liu, David S. Chi, Chuanfu Li, H. Kenton Hall, Denise M. Milhorn, and Guha Krishnaswamy

HIV-1 Tat protein-induced VCAM-1 expression in human pulmonary artery endothelial cells and its signaling
Am J Physiol Lung Cell Mol Physiol 289: L252-L260, 2005. First published April 1, 2005; doi:10.1152/ajplung.00200.2004 [Abstract] [Full Text] [PDF]  

Thomas A. Parker, Theresa R. Grover, John P. Kinsella, John R. Falck, and Steven H. Abman

Inhibition of 20-HETE abolishes the myogenic response during NOS antagonism in the ovine fetal pulmonary circulation
Am J Physiol Lung Cell Mol Physiol 289: L261-L267, 2005. First published April 8, 2005; doi:10.1152/ajplung.00315.2004 [Abstract] [Full Text] [PDF]  

Wen Ning, Augustine M. K. Choi, and Chaojun Li

Carbon monoxide inhibits IL-17-induced IL-6 production through the MAPK pathway in human pulmonary epithelial cells
Am J Physiol Lung Cell Mol Physiol 289: L268-L273, 2005; doi:10.1152/ajplung.00168.2004 [Abstract] [Full Text] [PDF]  

Hajer Debbabi, Shamik Ghosh, Arati B. Kamath, Jennifer Alt, Daphne E. deMello, Sarah Dunsmore, and Samuel M. Behar

Primary type II alveolar epithelial cells present microbial antigens to antigen-specific CD4⁺ T cells
Am J Physiol Lung Cell Mol Physiol 289: L274-L279, 2005. First published April 15, 2005; doi:10.1152/ajplung.00004.2005 [Abstract] [Full Text] [PDF]  

Akemi Nakatani-Okuda, Haruyasu Ueda, Shin-ichiro Kashiwamura, Atsuo Sekiyama, Akira Kubota, Yukihisa Fujita, Susumu Adachi, Yoshiyuki Tsuji, Takakuni Tanizawa, and Haruki Okamura

Protection against bleomycin-induced lung injury by IL-18 in mice
Am J Physiol Lung Cell Mol Physiol 289: L280-L287, 2005. First published March 25, 2005; doi:10.1152/ajplung.00380.2004 [Abstract] [Full Text] [PDF]  

Eugenia Mata-Greenwood, Albert Grobe, Sanjiv Kumar, Yelina Noskina, and Stephen M. Black

Cyclic stretch increases VEGF expression in pulmonary arterial smooth muscle cells via TGF-1 and reactive oxygen species: a requirement for NAD(P)H oxidase
Am J Physiol Lung Cell Mol Physiol 289: L288-L289, 2005. First published April 8, 2005; doi:10.1152/ajplung.00417.2004 [Abstract] [Full Text] [PDF]  

Alyson A. Miller, Alison A. Hislop, Patrick J. Vallance, and Sheila G. Haworth

Deletion of the eNOS gene has a greater impact on the pulmonary circulation of male than female mice
Am J Physiol Lung Cell Mol Physiol 289: L299-L366, 2005. First published April 8, 2005; doi:10.1152/ajplung.00022.2005 [Abstract] [Full Text] [PDF]  

Qin Yao, Musa A. Haxhiu, Syed I. Zaidi, Shijian Liu, Anjum Jafri, and Richard J. Martin

Hyperoxia enhances brain-derived neurotrophic factor and tyrosine kinase B receptor expression in peribronchial smooth muscle of neonatal rats
Am J Physiol Lung Cell Mol Physiol 289: L307-L314, 2005. First published April 8, 2005; doi:10.1152/ajplung.00030.2005 [Abstract] [Full Text] [PDF]  

Theresa R. Grover, Thomas A. Parker, Neil E. Markham, and Steven H. Abman

rhVEGF treatment preserves pulmonary vascular reactivity and structure in an experimental model of pulmonary hypertension in fetal sheep
Am J Physiol Lung Cell Mol Physiol 289: L315-L321, 2005. First published April 15, 2005; doi:10.1152/ajplung.00038.2005 [Abstract] [Full Text] [PDF]  

T. H. Thatcher, N. A. McHugh, R. W. Egan, R. W. Chapman, J. A. Hey, C. K. Turner, M. R. Redonnet, K. E. Seweryniak, P. J. Sime, and R. P. Phipps

Role of CXCR2 in cigarette smoke-induced lung inflammation
Am J Physiol Lung Cell Mol Physiol 289: L322-L328, 2005. First published April 15, 2005; doi:10.1152/ajplung.00039.2005 [Abstract] [Full Text] [PDF]  

Jordan D. Savov, David M. Brass, Barbara L. Lawson, Erin McElvania-Tekippe, Julia K. L. Walker, and David A. Schwartz

Toll-like receptor 4 antagonist (E5564) prevents the chronic airway response to inhaled lipopolysaccharide
Am J Physiol Lung Cell Mol Physiol 289: L329-L337, 2005. First published April 15, 2005; doi:10.1152/ajplung.00014.2005 [Abstract] [Full Text] [PDF]  

Xiao-Ru Yang, Mo-Jun Lin, Kay-Pong Yip, Loice H. Jeyakumar, Sidney Fleischer, George P. H. Leung, and James S. K. Sham

Multiple ryanodine receptor subtypes and heterogeneous ryanodine receptor-gated Ca²⁺ stores in pulmonary arterial smooth muscle cells
Am J Physiol Lung Cell Mol Physiol 289: L338-L348, 2005. First published April 29, 2005; doi:10.1152/ajplung.00328.2004 [Abstract] [Full Text] [PDF]  

Michael B. Maron, Hans G. Folkesson, Sonya M. Stader, and Jon M. Walro

PKA delivery to the distal lung air spaces increases alveolar liquid clearance after isoproterenol-induced alveolar epithelial PKA desensitization
Am J Physiol Lung Cell Mol Physiol 289: L349-L354, 2005. First published April 22, 2005; doi:10.1152/ajplung.00134.2004 [Abstract] [Full Text] [PDF]  

REPORTS:

Ippei Kuwahara, Erik P. Lillehoj, Akinori Hisatsune, Wenju Lu, Yoichiro Isohama, Takeshi Miyata, and K. Chul Kim

Neutrophil elastase stimulates MUC1 gene expression through increased Sp1 binding to the MUC1 promoter
Am J Physiol Lung Cell Mol Physiol 289: L355-L362, 2005. First published April 22, 2005; doi:10.1152/ajplung.00040.2005 [Abstract] [Full Text] [PDF]  

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