INVITED REVIEW:

Gye Young Park and John W. Christman

Involvement of cyclooxygenase-2 and prostaglandins in the molecular pathogenesis of inflammatory lung diseases
Am J Physiol Lung Cell Mol Physiol 290: L797-L805, 2006; doi:10.1152/ajplung.00513.2005 [Abstract] [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY:

Silvia Muro, Madalina Mateescu, Christine Gajewski, Mary Robinson, Vladimir R. Muzykantov, and Michael Koval

Control of intracellular trafficking of ICAM-1-targeted nanocarriers by endothelial Na⁺/H⁺ exchanger proteins
Am J Physiol Lung Cell Mol Physiol 290: L809-L817, 2006. First published November 18, 2005; doi:10.1152/ajplung.00311.2005 [Abstract] [Full Text] [PDF]  

Hortense Slevogt, Bernd Schmeck, Carola Jonatat, Janine Zahlten, Wiebke Beermann, Vincent van Laak, Bastian Opitz, Solveig Dietel, Philippe Dje N'Guessan, Stefan Hippenstiel, Norbert Suttorp, and Joachim Seybold

Moraxella catarrhalis induces inflammatory response of bronchial epithelial cells via MAPK and NF-B activation and histone deacetylase activity reduction
Am J Physiol Lung Cell Mol Physiol 290: L818-L826, 2006. First published January 6, 2006; doi:10.1152/ajplung.00428.2005 [Abstract] [Full Text] [PDF]  

EDITORIAL FOCUS:

Radu V. Stan

Endocytosis pathways in endothelium: how many?
Am J Physiol Lung Cell Mol Physiol 290: L806-L808, 2006; doi:10.1152/ajplung.00533.2005 [Full Text] [PDF]  

ARTICLES:

Silvia Carraro, Joseph Doherty, Khalequz Zaman, Iain Gainov, Ronald Turner, John Vaughan, John F. Hunt, Javier Márquez, and Benjamin Gaston

S-nitrosothiols regulate cell-surface pH buffering by airway epithelial cells during the human immune response to rhinovirus
Am J Physiol Lung Cell Mol Physiol 290: L827-L832, 2006; doi:10.1152/ajplung.00406.2005 [Abstract] [Full Text] [PDF]  

Jessica G. Moreland and Gail Bailey

Neutrophil transendothelial migration in vitro to Streptococcus pneumoniae is pneumolysin dependent
Am J Physiol Lung Cell Mol Physiol 290: L833-L840, 2006. First published December 9, 2005; doi:10.1152/ajplung.00333.2005 [Abstract] [Full Text] [PDF]  

Katharine A. Young, Charles Ivester, James West, Michelle Carr, and David M. Rodman

BMP signaling controls PASMC K_V channel expression in vitro and in vivo
Am J Physiol Lung Cell Mol Physiol 290: L841-L848, 2006. First published December 9, 2005; doi:10.1152/ajplung.00158.2005 [Abstract] [Full Text] [PDF]  

D. S. Allen-Gipson, J. Wong, J. R. Spurzem, J. H. Sisson, and T. A. Wyatt

Adenosine A_2A receptors promote adenosine-stimulated wound healing in bronchial epithelial cells
Am J Physiol Lung Cell Mol Physiol 290: L849-L855, 2006. First published December 16, 2005; doi:10.1152/ajplung.00373.2005 [Abstract] [Full Text] [PDF]  

Frank L. Lu, Richard A. Johnston, Lesley Flynt, Todd A. Theman, Raya D. Terry, Igor N. Schwartzman, Anna Lee, and Stephanie A. Shore

Increased pulmonary responses to acute ozone exposure in obese db/db mice
Am J Physiol Lung Cell Mol Physiol 290: L856-L865, 2006. First published December 22, 2005; doi:10.1152/ajplung.00386.2005 [Abstract] [Full Text] [PDF]  

Donald Massaro and Gloria DeCarlo Massaro

Estrogen receptor regulation of pulmonary alveolar dimensions: alveolar sexual dimorphism in mice
Am J Physiol Lung Cell Mol Physiol 290: L866-L870, 2006. First published December 16, 2005; doi:10.1152/ajplung.00396.2005 [Abstract] [Full Text] [PDF]  

Éric Careau, Léa-Isabelle Proulx, Philippe Pouliot, Annie Spahr, Véronique Turmel, and Élyse Y. Bissonnette

Antigen sensitization modulates alveolar macrophage functions in an asthma model
Am J Physiol Lung Cell Mol Physiol 290: L871-L879, 2006; doi:10.1152/ajplung.00219.2005 [Abstract] [Full Text] [PDF]  

Quiyang Zhang, Orson W. Moe, Joseph A. Garcia, and Connie C. W. Hsia

Regulated expression of hypoxia-inducible factors during postnatal and postpneumonectomy lung growth
Am J Physiol Lung Cell Mol Physiol 290: L880-L889, 2006. First published December 22, 2005; doi:10.1152/ajplung.00213.2005 [Abstract] [Full Text] [PDF]  

Felix R. Shardonofsky, Yassemi Capetanaki, and Aladin M. Boriek

Desmin modulates lung elastic recoil and airway responsiveness
Am J Physiol Lung Cell Mol Physiol 290: L890-L896, 2006. First published December 30, 2005; doi:10.1152/ajplung.00397.2005 [Abstract] [Full Text] [PDF]  

John A. Marwick, Christopher S. Stevenson, June Giddings, William MacNee, Keith Butler, Irfan Rahman, and Paul A. Kirkham

Cigarette smoke disrupts VEGF₁₆₅-VEGFR-2 receptor signaling complex in rat lungs and patients with COPD: morphological impact of VEGFR-2 inhibition
Am J Physiol Lung Cell Mol Physiol 290: L897-L908, 2006. First published December 16, 2005; doi:10.1152/ajplung.00116.2005 [Abstract] [Full Text] [PDF]  

Mark O. Aksoy, Yi Yang, Rong Ji, P. J. Reddy, Syed Shahabuddin, Judith Litvin, Thomas J. Rogers, and Steven G. Kelsen

CXCR3 surface expression in human airway epithelial cells: cell cycle dependence and effect on cell proliferation
Am J Physiol Lung Cell Mol Physiol 290: L909-L918, 2006. First published December 9, 2005; doi:10.1152/ajplung.00430.2005 [Abstract] [Full Text] [PDF]  

Aigul Moldobaeva, Laura E. Welsh-Servinsky, Larissa A. Shimoda, R. Scott Stephens, Alexander D. Verin, Rubin M. Tuder, and David B. Pearse

Role of protein kinase G in barrier-protective effects of cGMP in human pulmonary artery endothelial cells
Am J Physiol Lung Cell Mol Physiol 290: L919-L930, 2006. First published December 9, 2005; doi:10.1152/ajplung.00434.2005 [Abstract] [Full Text] [PDF]  

R. Vlahos, S. Bozinovski, J. E. Jones, J. Powell, J. Gras, A. Lilja, M. J. Hansen, R. C. Gualano, L. Irving, and G. P. Anderson

Differential protease, innate immunity, and NF-B induction profiles during lung inflammation induced by subchronic cigarette smoke exposure in mice
Am J Physiol Lung Cell Mol Physiol 290: L931-L945, 2006. First published December 16, 2005; doi:10.1152/ajplung.00201.2005 [Abstract] [Full Text] [PDF]  

Ryoko Yumoto, Hiromi Nishikawa, Miho Okamoto, Hirokazu Katayama, Junya Nagai, and Mikihisa Takano

Clathrin-mediated endocytosis of FITC-albumin in alveolar type II epithelial cell line RLE-6TN
Am J Physiol Lung Cell Mol Physiol 290: L946-L955, 2006. First published December 16, 2005; doi:10.1152/ajplung.00173.2005 [Abstract] [Full Text] [PDF]  

Kristen D. Singleton and Paul E. Wischmeyer

Effects of HSP70.1/3 gene knockout on acute respiratory distress syndrome and the inflammatory response following sepsis
Am J Physiol Lung Cell Mol Physiol 290: L956-L961, 2006. First published December 16, 2005; doi:10.1152/ajplung.00466.2005 [Abstract] [Full Text] [PDF]  

Michael P. Mendez, Susan B. Morris, Steven Wilcoxen, Elizabeth Greeson, Bethany Moore, and Robert Paine, III

Shedding of soluble ICAM-1 into the alveolar space in murine models of acute lung injury
Am J Physiol Lung Cell Mol Physiol 290: L962-L970, 2006. First published December 22, 2005; doi:10.1152/ajplung.00352.2005 [Abstract] [Full Text] [PDF]  

Maiko Moriyama, Satoru Fukuyama, Hiromasa Inoue, Takafumi Matsumoto, Takahiro Sato, Kentaro Tanaka, Ichiko Kinjyo, Tatsuhiko Kano, Akihiko Yoshimura, and Masayasu Kojima

The neuropeptide neuromedin U activates eosinophils and is involved in allergen-induced eosinophilia
Am J Physiol Lung Cell Mol Physiol 290: L971-L977, 2006. First published December 22, 2005; doi:10.1152/ajplung.00345.2005 [Abstract] [Full Text] [PDF] [Supplemental Table]  

Yuko Arita, S. Hella Harkness, Jeffrey A. Kazzaz, Hshi-chi Koo, Ansamma Joseph, J.Andres Melendez, Jonathan M. Davis, A. Chander, and Yuchi Li

Mitochondrial localization of catalase provides optimal protection from H₂O₂-induced cell death in lung epithelial cells
Am J Physiol Lung Cell Mol Physiol 290: L978-L986, 2006. First published December 30, 2005; doi:10.1152/ajplung.00296.2005 [Abstract] [Full Text] [PDF]  

J. Moisan, P. Camateros, T. Thuraisingam, D. Marion, H. Koohsari, P. Martin, M. L. Boghdady, A. Ding, M. Gaestel, M. C. Guiot, J. G. Martin, and D. Radzioch

TLR7 ligand prevents allergen-induced airway hyperresponsiveness and eosinophilia in allergic asthma by a MYD88-dependent and MK2-independent pathway
Am J Physiol Lung Cell Mol Physiol 290: L987-L995, 2006. First published December 16, 2005; doi:10.1152/ajplung.00440.2005 [Abstract] [Full Text] [PDF]  

Sabah N. A. Hussain, Ghassan Matar, Esther Barreiro, Maria Florian, Maziar Divangahi, and Theodoros Vassilakopoulos

Modifications of proteins by 4-hydroxy-2-nonenal in the ventilatory muscles of rats
Am J Physiol Lung Cell Mol Physiol 290: L996-L1003, 2006; doi:10.1152/ajplung.00337.2005 [Abstract] [Full Text] [PDF]  

Huang-Ping Yu, Ya-Ching Hsieh, Takao Suzuki, Tomoharu Shimizu, Mashkoor A. Choudhry, Martin G. Schwacha, and Irshad H. Chaudry

Salutary effects of estrogen receptor- agonist on lung injury after trauma-hemorrhage
Am J Physiol Lung Cell Mol Physiol 290: L1004-L1009, 2006. First published December 16, 2005; doi:10.1152/ajplung.00504.2005 [Abstract] [Full Text] [PDF]  

Grith L. Sørensen, Jacob v. B. Hjelmborg, Kirsten O. Kyvik, Mogens Fenger, Anette Høj, Christian Bendixen, Thorkild I. A. Sørensen, and Uffe Holmskov

Genetic and environmental influences of surfactant protein D serum levels
Am J Physiol Lung Cell Mol Physiol 290: L1010-L1017, 2006. First published December 16, 2005; doi:10.1152/ajplung.00487.2005 [Abstract] [Full Text] [PDF]  

Miwa Taniguchi, Young Lan Kwak, Keith A. Jones, David O. Warner, and William J. Perkins

Nitric oxide sensitivity in pulmonary artery and airway smooth muscle: a possible role for cGMP responsiveness
Am J Physiol Lung Cell Mol Physiol 290: L1018-L1027, 2006. First published December 2, 2005; doi:10.1152/ajplung.00402.2005 [Abstract] [Full Text] [PDF]  

Yu-Mee Kim, William Reed, Weidong Wu, Philip A. Bromberg, Lee M. Graves, and James M. Samet

Zn²⁺-induced IL-8 expression involves AP-1, JNK, and ERK activities in human airway epithelial cells
Am J Physiol Lung Cell Mol Physiol 290: L1028-L1035, 2006. First published December 22, 2005; doi:10.1152/ajplung.00479.2005 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY:

Olivier Bonneau, Daniel Wyss, Stephane Ferretti, Clare Blaydon, Christopher S. Stevenson, and Alexandre Trifilieff

Effect of adenosine A_2A receptor activation in murine models of respiratory disorders
Am J Physiol Lung Cell Mol Physiol 290: L1036-L1043, 2006. First published December 9, 2005; doi:10.1152/ajplung.00422.2005 [Abstract] [Full Text] [PDF]  

CORRIGENDA:

Corrigendum
Am J Physiol Lung Cell Mol Physiol 290: L1044-L1044, 2006; doi:10.1152/ajplung.00043.2006 [Full Text] [PDF]  

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