EDITORIALS:

Lorraine B. Ware

Modeling human lung disease in animals
Am J Physiol Lung Cell Mol Physiol 294: L149-L150, 2008. First published November 16, 2007; doi:10.1152/ajplung.00472.2007 [Full Text] [PDF]  

INVITED REVIEW:

Bethany B. Moore and Cory M. Hogaboam

Murine models of pulmonary fibrosis
Am J Physiol Lung Cell Mol Physiol 294: L152-L160, 2008. First published November 9, 2007; doi:10.1152/ajplung.00313.2007 [Abstract] [Full Text] [PDF]  

Anna L. Lagan, Daniel D. Melley, Timothy W. Evans, and Gregory J. Quinlan

Pathogenesis of the systemic inflammatory syndrome and acute lung injury: role of iron mobilization and decompartmentalization
Am J Physiol Lung Cell Mol Physiol 294: L161-L174, 2008. First published November 30, 2007; doi:10.1152/ajplung.00169.2007 [Abstract] [Full Text] [PDF]  

EDITORIAL FOCUS:

Jack Gauldie and Martin Kolb

Animal models of pulmonary fibrosis: how far from effective reality?
Am J Physiol Lung Cell Mol Physiol 294: L151-L151, 2008. First published December 21, 2007; doi:10.1152/ajplung.00520.2007 [Full Text] [PDF]  

Rachel Zemans and Gregory P. Downey

Role of caveolin-1 in regulation of inflammation: different strokes for different folks
Am J Physiol Lung Cell Mol Physiol 294: L175-L177, 2008. First published November 30, 2007; doi:10.1152/ajplung.00488.2007 [Full Text] [PDF]  

Guochang Hu, Richard D. Ye, Mary C. Dinauer, Asrar B. Malik, and Richard D. Minshall

Neutrophil caveolin-1 expression contributes to mechanism of lung inflammation and injury
Am J Physiol Lung Cell Mol Physiol 294: L178-L186, 2008. First published November 9, 2007; doi:10.1152/ajplung.00263.2007 [Abstract] [Full Text] [PDF]  

Paul E. Moore

Exploration of the β₂-adrenergic receptor regulatory regions: the next step in the holy grail of asthma pharmacogenetics research
Am J Physiol Lung Cell Mol Physiol 294: L187-L189, 2008. First published December 7, 2007; doi:10.1152/ajplung.00494.2007 [Full Text] [PDF]  

Alfredo Panebra, Mary Rose Schwarb, Steven M. Swift, Scott T. Weiss, Eugene R. Bleecker, Gregory A. Hawkins, and Stephen B. Liggett

Variable-length poly-C tract polymorphisms of the β₂-adrenergic receptor 3'-UTR alter expression and agonist regulation
Am J Physiol Lung Cell Mol Physiol 294: L190-L195, 2008. First published November 16, 2007; doi:10.1152/ajplung.00277.2007 [Abstract] [Full Text] [PDF]  

ARTICLES:

Hiroaki Mori, Takashi Nose, Kouki Ishitani, Satoshi Kasagi, Sanae Souma, Taeko Akiyoshi, Yuzo Kodama, Takanori Mori, Miwa Kondo, Shinichi Sasaki, Akihiko Iwase, Kazuhisa Takahashi, Yoshinosuke Fukuchi, and Kuniaki Seyama

Phosphodiesterase 4 inhibitor GPD-1116 markedly attenuates the development of cigarette smoke-induced emphysema in senescence-accelerated mice P1 strain
Am J Physiol Lung Cell Mol Physiol 294: L196-L204, 2008. First published November 9, 2007; doi:10.1152/ajplung.00173.2007 [Abstract] [Full Text] [PDF]  

Patrick J. McNamara, Prashanth Murthy, Crystal Kantores, Lilian Teixeira, Doreen Engelberts, Todd van Vliet, Brian P. Kavanagh, and Robert P. Jankov

Acute vasodilator effects of Rho-kinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide
Am J Physiol Lung Cell Mol Physiol 294: L205-L213, 2008. First published November 21, 2007; doi:10.1152/ajplung.00234.2007 [Abstract] [Full Text] [PDF]  

Kathleen J. Haley, Mary E. Sunday, Yolanda Porrata, Colleen Kelley, Anne Twomey, Aliakbar Shahsafaei, Benjamin Galper, Larry A. Sonna, and Craig M. Lilly

Ontogeny of the eotaxins in human lung
Am J Physiol Lung Cell Mol Physiol 294: L214-L224, 2008. First published November 30, 2007; doi:10.1152/ajplung.00086.2007 [Abstract] [Full Text] [PDF]  

Hyeon-Soo Lee, Yulian Wang, Benjamin S. Maciejewski, Kenny Esho, Christiaan Fulton, Surendra Sharma, and Juan Sanchez-Esteban

Interleukin-10 protects cultured fetal rat type II epithelial cells from injury induced by mechanical stretch
Am J Physiol Lung Cell Mol Physiol 294: L225-L232, 2008. First published December 7, 2007; doi:10.1152/ajplung.00370.2007 [Abstract] [Full Text] [PDF]  

Robert P. Jankov, Crystal Kantores, Jingyi Pan, and Jaques Belik

Contribution of xanthine oxidase-derived superoxide to chronic hypoxic pulmonary hypertension in neonatal rats
Am J Physiol Lung Cell Mol Physiol 294: L233-L245, 2008. First published December 14, 2007; doi:10.1152/ajplung.00166.2007 [Abstract] [Full Text] [PDF]  

Johannes C. Schittny, Sonja I. Mund, and Marco Stampanoni

Evidence and structural mechanism for late lung alveolarization
Am J Physiol Lung Cell Mol Physiol 294: L246-L254, 2008. First published November 21, 2007; doi:10.1152/ajplung.00296.2007 [Abstract] [Full Text] [PDF] [Supplemental Video]  

James C. Lee, Faiz Bhora, Jing Sun, Guanjun Cheng, Evguenia Arguiri, Charalambos C. Solomides, Shampa Chatterjee, and Melpo Christofidou-Solomidou

Dietary flaxseed enhances antioxidant defenses and is protective in a mouse model of lung ischemia-reperfusion injury
Am J Physiol Lung Cell Mol Physiol 294: L255-L265, 2008. First published December 14, 2007; doi:10.1152/ajplung.00138.2007 [Abstract] [Full Text] [PDF] [Supplemental Materials and Methods and Results]  

B. Troyanovsky, D. F. Alvarez, J. A. King, and K. L. Schaphorst

Thrombin enhances the barrier function of rat microvascular endothelium in a PAR-1-dependent manner
Am J Physiol Lung Cell Mol Physiol 294: L266-L275, 2008. First published December 14, 2007; doi:10.1152/ajplung.00107.2007 [Abstract] [Full Text] [PDF]  

Edda Spiekerkoetter, Cristina Maria Alvira, Yu-Mee Kim, Alexandra Bruneau, Katie Lynn Pricola, Lingli Wang, Noona Ambartsumian, and Marlene Rabinovitch

Reactivation of HV68 induces neointimal lesions in pulmonary arteries of S100A4/Mts1-overexpressing mice in association with degradation of elastin
Am J Physiol Lung Cell Mol Physiol 294: L276-L289, 2008. First published December 14, 2007; doi:10.1152/ajplung.00414.2007 [Abstract] [Full Text] [PDF]  

Alonso G. P. Guedes, Joseph A. Jude, Jaime Paulin, Hirohito Kita, Frances E. Lund, and Mathur S. Kannan

Role of CD38 in TNF--induced airway hyperresponsiveness
Am J Physiol Lung Cell Mol Physiol 294: L290-L299, 2008. First published November 30, 2007; doi:10.1152/ajplung.00367.2007 [Abstract] [Full Text] [PDF]  

Bodil Petersen, Kenneth D. Bloch, Fumito Ichinose, Hae-Sook Shin, Misako Shigematsu, Aranya Bagchi, Warren M. Zapol, and Judith Hellman

Activation of Toll-like receptor 2 impairs hypoxic pulmonary vasoconstriction in mice
Am J Physiol Lung Cell Mol Physiol 294: L300-L308, 2008. First published November 30, 2007; doi:10.1152/ajplung.00243.2007 [Abstract] [Full Text] [PDF]  

E. Miles Whitman, Sarah Pisarcik, Trevor Luke, Michele Fallon, Jian Wang, J. T. Sylvester, Gregg L. Semenza, and Larissa A. Shimoda

Endothelin-1 mediates hypoxia-induced inhibition of voltage-gated K⁺ channel expression in pulmonary arterial myocytes
Am J Physiol Lung Cell Mol Physiol 294: L309-L318, 2008. First published December 7, 2007; doi:10.1152/ajplung.00091.2007 [Abstract] [Full Text] [PDF]  

Irina A. Kolosova, Tamara Mirzapoiazova, Liliana Moreno-Vinasco, Saad Sammani, Joe G. N. Garcia, and Alexander D. Verin

Protective effect of purinergic agonist ATPS against acute lung injury
Am J Physiol Lung Cell Mol Physiol 294: L319-L324, 2008. First published November 9, 2007; doi:10.1152/ajplung.00283.2007 [Abstract] [Full Text] [PDF]  

Sandra R. Bates, Chandra Dodia, Jian-Qin Tao, and Aron B. Fisher

Surfactant protein-A plays an important role in lung surfactant clearance: evidence using the surfactant protein-A gene-targeted mouse
Am J Physiol Lung Cell Mol Physiol 294: L325-L333, 2008. First published December 14, 2007; doi:10.1152/ajplung.00341.2007 [Abstract] [Full Text] [PDF]  

Christophe Quesnel, Sylvain Marchand-Adam, Aurélie Fabre, Joëlle Marchal-Somme, Ivan Philip, Sigismond Lasocki, Véronique Leçon, Bruno Crestani, and Monique Dehoux

Regulation of hepatocyte growth factor secretion by fibroblasts in patients with acute lung injury
Am J Physiol Lung Cell Mol Physiol 294: L334-L343, 2008. First published December 7, 2007; doi:10.1152/ajplung.00096.2007 [Abstract] [Full Text] [PDF]  

Rogier M. Determann, Esther K. Wolthuis, Goda Choi, Paul Bresser, Alfred Bernard, Rene Lutter, and Marcus J. Schultz

Lung epithelial injury markers are not influenced by use of lower tidal volumes during elective surgery in patients without preexisting lung injury
Am J Physiol Lung Cell Mol Physiol 294: L344-L350, 2008. First published December 14, 2007; doi:10.1152/ajplung.00268.2007 [Abstract] [Full Text] [PDF]  

Elizabeth M. Wagner, Jesús Sánchez, Jessica Y. McClintock, John Jenkins, and Aigul Moldobaeva

Inflammation and ischemia-induced lung angiogenesis
Am J Physiol Lung Cell Mol Physiol 294: L351-L357, 2008. First published December 21, 2007; doi:10.1152/ajplung.00369.2007 [Abstract] [Full Text] [PDF]  

Klaus Unfried, Ulrich Sydlik, Katrin Bierhals, Alexander Weissenberg, and Josef Abel

Carbon nanoparticle-induced lung epithelial cell proliferation is mediated by receptor-dependent Akt activation
Am J Physiol Lung Cell Mol Physiol 294: L358-L367, 2008. First published December 14, 2007; doi:10.1152/ajplung.00323.2007 [Abstract] [Full Text] [PDF]  

Theo J. Moraes, Raiza Martin, Jonathan D. Plumb, Eric Vachon, Cheryl M. Cameron, Ali Danesh, David J. Kelvin, Wolfram Ruf, and Gregory P. Downey

Role of PAR2 in murine pulmonary pseudomonal infection
Am J Physiol Lung Cell Mol Physiol 294: L368-L377, 2008. First published December 14, 2007; doi:10.1152/ajplung.00036.2007 [Abstract] [Full Text] [PDF]  

Gary C. Sieck, Thomas A. White, Michael A. Thompson, Christina M. Pabelick, Mark E. Wylam, and Y. S. Prakash

Regulation of store-operated Ca²⁺ entry by CD38 in human airway smooth muscle
Am J Physiol Lung Cell Mol Physiol 294: L378-L385, 2008. First published January 4, 2008; doi:10.1152/ajplung.00394.2007 [Abstract] [Full Text] [PDF]  

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