INVITED REVIEW:

Christian Mühlfeld, Barbara Rothen-Rutishauser, Fabian Blank, Dimitri Vanhecke, Matthias Ochs, and Peter Gehr

Interactions of nanoparticles with pulmonary structures and cellular responses
Am J Physiol Lung Cell Mol Physiol 294: L817-L829, 2008. First published February 8, 2008; doi:10.1152/ajplung.00442.2007 [Abstract] [Full Text] [PDF] [Supplemental Figure and Video]  

Adel Boueiz, Mahendra Damarla, and Paul M. Hassoun

Xanthine oxidoreductase in respiratory and cardiovascular disorders
Am J Physiol Lung Cell Mol Physiol 294: L830-L840, 2008. First published March 14, 2008; doi:10.1152/ajplung.00007.2008 [Abstract] [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY:

Julie A. Bastarache, Ling Wang, Zhengming Wang, Kurt H. Albertine, Michael A. Matthay, and Lorraine B. Ware

Intra-alveolar tissue factor pathway inhibitor is not sufficient to block tissue factor procoagulant activity
Am J Physiol Lung Cell Mol Physiol 294: L874-L881, 2008. First published February 29, 2008; doi:10.1152/ajplung.00372.2007 [Abstract] [Full Text] [PDF]  

EDITORIAL FOCUS:

Hong Pyo Kim and Augustine M. K. Choi

Caveolin-1 stops profibrogenic signaling?
Am J Physiol Lung Cell Mol Physiol 294: L841-L842, 2008. First published February 22, 2008; doi:10.1152/ajplung.00073.2008 [Full Text] [PDF]  

Elena Tourkina, Mathieu Richard, Pal Gööz, Michael Bonner, Jaspreet Pannu, Russell Harley, Pascal N. Bernatchez, William C. Sessa, Richard M. Silver, and Stanley Hoffman

Antifibrotic properties of caveolin-1 scaffolding domain in vitro and in vivo
Am J Physiol Lung Cell Mol Physiol 294: L843-L861, 2008. First published January 18, 2008; doi:10.1152/ajplung.00295.2007 [Abstract] [Full Text] [PDF]  

Stefan W. Ryter and Augustine M. K. Choi

Caveolin-1: a critical regulator of pulmonary vascular architecture and nitric oxide bioavailability in pulmonary hypertension
Am J Physiol Lung Cell Mol Physiol 294: L862-L864, 2008. First published February 22, 2008; doi:10.1152/ajplung.00074.2008 [Full Text] [PDF]  

Nikolaos A. Maniatis, Vasily Shinin, Dean E. Schraufnagel, Shigenori Okada, Stephen M. Vogel, Asrar B. Malik, and Richard D. Minshall

Increased pulmonary vascular resistance and defective pulmonary artery filling in caveolin-1^–/– mice
Am J Physiol Lung Cell Mol Physiol 294: L865-L873, 2008. First published January 11, 2008; doi:10.1152/ajplung.00079.2007 [Abstract] [Full Text] [PDF] [Supplemental Figure]  

ARTICLES:

Saeko Takahashi, Hidetoshi Nakamura, Makoto Seki, Yoshiki Shiraishi, Miyuki Yamamoto, Momoyo Furuuchi, Takahiro Nakajima, Shuko Tsujimura, Toru Shirahata, Miho Nakamura, Naoto Minematsu, Motohiro Yamasaki, Hiroki Tateno, and Akitoshi Ishizaka

Reversal of elastase-induced pulmonary emphysema and promotion of alveolar epithelial cell proliferation by simvastatin in mice
Am J Physiol Lung Cell Mol Physiol 294: L882-L890, 2008. First published February 29, 2008; doi:10.1152/ajplung.00238.2007 [Abstract] [Full Text] [PDF]  

Jami E. Milam, Venkateshwar G. Keshamouni, Sem H. Phan, Biao Hu, Srinivasa R. Gangireddy, Cory M. Hogaboam, Theodore J. Standiford, Victor J. Thannickal, and Raju C. Reddy

PPAR- agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis
Am J Physiol Lung Cell Mol Physiol 294: L891-L901, 2008. First published December 27, 2007; doi:10.1152/ajplung.00333.2007 [Abstract] [Full Text] [PDF]  

Meetha Medhora, Yuenmu Chen, Stephanie Gruenloh, Daniel Harland, Sreedhar Bodiga, Jacek Zielonka, Debebe Gebremedhin, Ying Gao, John R. Falck, Siddam Anjaiah, and Elizabeth R. Jacobs

20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells
Am J Physiol Lung Cell Mol Physiol 294: L902-L911, 2008. First published February 22, 2008; doi:10.1152/ajplung.00278.2007 [Abstract] [Full Text] [PDF]  

Ping-Chia Li, Wen-Chung Chen, Li-Ching Chang, and Shao-Chieh Lin

Substance P acts via the neurokinin receptor 1 to elicit bronchoconstriction, oxidative stress, and upregulated ICAM-1 expression after oil smoke exposure
Am J Physiol Lung Cell Mol Physiol 294: L912-L920, 2008. First published March 7, 2008; doi:10.1152/ajplung.00443.2007 [Abstract] [Full Text] [PDF]  

Yong Chan Lee, Chun-Yu Chuang, Pak-Kei Lee, Jin-Soo Lee, Richart W. Harper, Alan B. Buckpitt, Reen Wu, and Karen Oslund

TRX-ASK1-JNK signaling regulation of cell density-dependent cytotoxicity in cigarette smoke-exposed human bronchial epithelial cells
Am J Physiol Lung Cell Mol Physiol 294: L921-L931, 2008. First published February 15, 2008; doi:10.1152/ajplung.00250.2007 [Abstract] [Full Text] [PDF]  

Mike M. Myerburg, Erin E. McKenna, Cliff J. Luke, Raymond A. Frizzell, Thomas R. Kleyman, and Joseph M. Pilewski

Prostasin expression is regulated by airway surface liquid volume and is increased in cystic fibrosis
Am J Physiol Lung Cell Mol Physiol 294: L932-L941, 2008. First published February 29, 2008; doi:10.1152/ajplung.00437.2007 [Abstract] [Full Text] [PDF]  

Sean G. Brown, Michael Gallacher, Richard E. Olver, and Stuart M. Wilson

The regulation of selective and nonselective Na⁺ conductances in H441 human airway epithelial cells
Am J Physiol Lung Cell Mol Physiol 294: L942-L954, 2008. First published February 29, 2008; doi:10.1152/ajplung.00240.2007 [Abstract] [Full Text] [PDF]  

Mahroo Mofarrahi, Thamir Nouh, Salman Qureshi, Loic Guillot, Dominique Mayaki, and Sabah N. A. Hussain

Regulation of angiopoietin expression by bacterial lipopolysaccharide
Am J Physiol Lung Cell Mol Physiol 294: L955-L963, 2008. First published February 29, 2008; doi:10.1152/ajplung.00449.2007 [Abstract] [Full Text] [PDF]  

Lu Wang, Valeria Pozzato, Graziella Turato, Aasakiran Madamanchi, Thomas M. Murphy, and Pasquale Chitano

Reduced spontaneous relaxation in immature guinea pig airway smooth muscle is associated with increased prostanoid release
Am J Physiol Lung Cell Mol Physiol 294: L964-L973, 2008. First published March 7, 2008; doi:10.1152/ajplung.00401.2007 [Abstract] [Full Text] [PDF]  

Adam A. Maruscak, Daniel W. Vockeroth, Brandon Girardi, Tanya Sheikh, Fred Possmayer, James F. Lewis, and Ruud A. W. Veldhuizen

Alterations to surfactant precede physiological deterioration during high tidal volume ventilation
Am J Physiol Lung Cell Mol Physiol 294: L974-L983, 2008. First published March 14, 2008; doi:10.1152/ajplung.00528.2007 [Abstract] [Full Text] [PDF]  

Ivan T. Demchenko, Dmitriy N. Atochin, Diana R. Gutsaeva, Ryan R. Godfrey, Paul L. Huang, Claude A. Piantadosi, and Barry W. Allen

Contributions of nitric oxide synthase isoforms to pulmonary oxygen toxicity, local vs. mediated effects
Am J Physiol Lung Cell Mol Physiol 294: L984-L990, 2008. First published March 7, 2008; doi:10.1152/ajplung.00420.2007 [Abstract] [Full Text] [PDF]  

Donald Massaro and Gloria DeCarlo Massaro

Apoe^tm1Unc mice have impaired alveologenesis, low lung function, and rapid loss of lung function
Am J Physiol Lung Cell Mol Physiol 294: L991-L997, 2008. First published March 14, 2008; doi:10.1152/ajplung.00013.2008 [Abstract] [Full Text] [PDF]  

Amit Kulkarni and Kumuda C. Das

Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation
Am J Physiol Lung Cell Mol Physiol 294: L998-L1006, 2008. First published March 14, 2008; doi:10.1152/ajplung.00004.2008 [Abstract] [Full Text] [PDF]  

Mikyung Yang, Xueqin Ding, and Paul A. Murray

Differential effects of intravenous anesthetics on capacitative calcium entry in human pulmonary artery smooth muscle cells
Am J Physiol Lung Cell Mol Physiol 294: L1007-L1012, 2008. First published March 14, 2008; doi:10.1152/ajplung.00171.2007 [Abstract] [Full Text] [PDF]  

Jason E. Lang, Erin S. Williams, Joseph P. Mizgerd, and Stephanie A. Shore

Effect of obesity on pulmonary inflammation induced by acute ozone exposure: role of interleukin-6
Am J Physiol Lung Cell Mol Physiol 294: L1013-L1020, 2008. First published March 21, 2008; doi:10.1152/ajplung.00122.2007 [Abstract] [Full Text] [PDF]  

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